Semmelweis proposed washing hands (in a chlorine solution with a low pH) could cut down on “childbed fever” (once with a mortality of 10 – 35%). Born in 1818 in what is now Budapest, Hungary. Ignaz Semmelweis: The “savior of mothers”. His success (asides from his prowess as a surgeon) was often related to believing in asepsis rather than antisepsis (a clean space instead of sterilizing to disinfect). Became a surgeon who became famous for being able to perform ovariectomies, a once 90% fatal operation. Lawson Tait: Born in 1845 (Edinburgh, Scotland). Who else has made significant contributions? He used carbolic acid (now known as phenol) to sterilize wounds.Ĭ. He recognized without skin to protect the wound, infection could come from the environment around him. Reading prior papers from Louis Pasteur gave Lister an idea that whatever caused fermentation (chemical breakdown by microorganisms) would also be involved in wound sepsis (life-threatening illness caused by your body's response to an infection). It had been previously theorized that germs could cause disease but it wasn’t understood in terms of wounds and infection. Half of surgery patients died because of infection. How did Joseph Lister contribute to sterility? The 1800’s were particularly unforgiving in terms of terms of surgery. He was well known for his interested in inflammation, reaction of the immune system to foreign bodies.ī. Lister became a surgeon by studying at the University College of the University of London. His father was a Fellow of the Royal Society for study of red blood cells and creating lenses to view them. Lister was born in Essex, England in 1827. Who was Joseph Lister? Commonly referred to as the father of modern surgery. Now I’m at a loss for what has happened because I’ve failed to be sterile and controlled the variable of extra pathogens in my experiment.Ģ) Joseph Lister and the development of sterility:Ī. What I don’t know is that the virus can’t kill the cells, but bacteria that is accidentally mixed in with the virus kills the cells. I’m in lab, infecting cells with a virus. You control for this by using other electronics that you know work. Now you don’t know if the electricity doesn’t work, the lamp doesn’t work, or the lightbulb is burned out. When you plug in a lamp, it doesn’t light up. You move into a new apartment and want to know if the electricity is working. Your friend is a magician you don’t know whether you’re losing because the cards aren’t in your favor or because you’re being tricked by sleight-of-hand. Say you’re at a friend’s place playing blackjack and you continuously keep losing. Why should we be sterile in scientific research or in medical fields? There are always variables that are inherent to everything. This definition can be finicky depending on how some organisms may not experience disease or individuals in a microorganism population that are less capable of causing disease. What is a pathogen? A microorganism that can cause or will cause disease – also defined as a microbe that will cause damage in a host. As simple as trying to avoid allowing fungus to grow in your bread or yogurt and spoil your food to as complicated as trying to prevent a virus from getting out of a biohazardous facility.ī. Aseptic technique is designed to provide a barrier between the microrganisms in the environment and some form of a sterile medium that one is working in. Sterility and aseptic technique: Incapable of producing offspring free from living germs or microorganisms.
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